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Head-to-head · WeighScore

Loop Health vs Metabolyz

Loop Health
Graded #114

Higher grade

vs+10.399999999999999
Metabolyz
Graded #339

Lower grade

The verdict

Loop Health takes it — 70/100 to 59.6/100.

Loop Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLoop Health +34
79
45
Dose & formulationLoop Health +24
64
40
Clinical oversightMetabolyz +2
79
81
Labs & monitoringLoop Health +10
73
63
FulfillmentMetabolyz +24
62
86
Contract termsMetabolyz +14
41
55
Loop Health · left barMetabolyz · right bar

The numbers

MetricLoop HealthMetabolyz
WeighScore70/10059.6/100
GradeCC
Scorecard rank#114#339
Semaglutide$79/mo (plus a separate fee, compounded)Not disclosed
Tirzepatide$125/mo (annual plan, plus a separate fee, compounded)Not disclosed
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Loop Health

Graded #114 · C

Strengths

  • Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
  • Low membership entry point ($79/mo)
  • Annual plan includes monthly 'research credit' toward compounds
  • Explicit compounded-drug FDA disclaimer on-site

Where it loses points

  • Per-dose GLP-1 drug pricing not transparent on public site (compounds billed separately by pharmacy)
  • States-served list not enumerated — only 'select U.S. states'
  • Platform explicitly 'is not a healthcare provider' — relies on independent provider network
  • No LegitScript number disclosed on homepage
Metabolyz

Graded #339 · C

Strengths

  • Three GLP-1 programs: standard semaglutide, dual-agonist tirzepatide, and a microdose protocol for near-goal or dose-sensitive patients
  • Nutrition, movement, and lifestyle coaching included in all programs at no extra charge
  • Medication compounded in licensed 503A/503B US pharmacies with temperature-controlled, unmarked direct-to-door delivery
  • Licensed provider supervision with direct messaging access and structured check-ins throughout
  • Telehealth across all 50 states; BMI 27+ eligibility (25+ with weight-related condition)

Where it loses points

  • Pricing is fully gated — not disclosed until after consultation, preventing upfront cost comparison
  • Compounded GLP-1 only — no brand-name options (Wegovy, Zepbound) available
  • No LegitScript certification or named medical leadership found on public-facing pages
  • Labs not mentioned as included — unclear whether baseline or follow-up bloodwork is offered
  • Newer brand with no external reviews, published outcomes data, or notable accreditations

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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