Head-to-head · WeighScore
Loop Health vs Lyfe Rx
The verdict
Loop Health takes it — 70/100 to 58.3/100.
Loop Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Loop Health | Lyfe Rx |
|---|---|---|
| WeighScore | 70/100 | 58.3/100 |
| Grade | C | C |
| Scorecard rank | #112 | #375 |
| Semaglutide | $79/mo (plus a separate fee, compounded) | $225/mo (compounded) |
| Tirzepatide | $125/mo (annual plan, plus a separate fee, compounded) | $299/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #112 · C
Strengths
- Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
- Low membership entry point ($79/mo)
- Annual plan includes monthly 'research credit' toward compounds
- Explicit compounded-drug FDA disclaimer on-site
Where it loses points
- Per-dose GLP-1 drug pricing not transparent on public site (compounds billed separately by pharmacy)
- States-served list not enumerated — only 'select U.S. states'
- Platform explicitly 'is not a healthcare provider' — relies on independent provider network
- No LegitScript number disclosed on homepage
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.