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Head-to-head · WeighScore

LillyDirect Foundayo vs WePeptideRx

LillyDirect Foundayo
Graded #173

Higher grade

vs+5.800000000000004
WePeptideRx
Graded #297

Lower grade

The verdict

LillyDirect Foundayo takes it — 67.2/100 to 61.4/100.

LillyDirect Foundayo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Eli Lilly's manufacturer direct-pay channel for Foundayo (orforglipron), the first oral GLP-1 pill for weight loss.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLillyDirect Foundayo +24
72
48
Dose & formulationWePeptideRx +5
59
64
Clinical oversightWePeptideRx +3
78
81
Labs & monitoringWePeptideRx +1
52
53
FulfillmentLillyDirect Foundayo +13
80
67
Contract termsEven
55
55
LillyDirect Foundayo · left barWePeptideRx · right bar

The numbers

MetricLillyDirect FoundayoWePeptideRx
WeighScore67.2/10061.4/100
GradeCC
Scorecard rank#173#297
SemaglutideNot disclosed$249/mo (compounded)
TirzepatideNot disclosed$249/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
LillyDirect Foundayo

Graded #173 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow
WePeptideRx

Graded #297 · C

Strengths

  • Pre-mixed ready-to-inject delivery skips the vial reconstitution and sharps hassle of most compounded providers
  • Microdose protocols (0.05–0.25 mg sema, 0.5–2.5 mg tirz) suit ultra-low-dose maintenance patients — uncommon in DTC
  • 12+ programs under one platform — GLP-1 plus longevity, sexual wellness, and hair
  • Physical Boca Raton address, phone, and business hours listed
  • LegitScript Certified and publishes the FDA disclaimer

Where it loses points

  • Pharmacy partner not named
  • 48-state claim, but the specific state list isn't shown on the homepage
  • Medical director not named on the homepage
  • Telemedicine is outsourced to a third-party provider network rather than in-house staff
  • Corporate legal entity and arbitration venue not disclosed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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