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Head-to-head · WeighScore

LillyDirect Foundayo vs Vital Harmony Rx

LillyDirect Foundayo
Graded #165

Higher grade

vs+15.5
Vital Harmony Rx
Graded #484

Lower grade

The verdict

LillyDirect Foundayo takes it — 67.2/100 to 51.7/100.

LillyDirect Foundayo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Eli Lilly's manufacturer direct-pay channel for Foundayo (orforglipron), the first oral GLP-1 pill for weight loss.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLillyDirect Foundayo +27
72
45
Dose & formulationLillyDirect Foundayo +19
59
40
Clinical oversightLillyDirect Foundayo +13
78
65
Labs & monitoringLillyDirect Foundayo +2
52
50
FulfillmentLillyDirect Foundayo +17
80
63
Contract termsEven
55
55
LillyDirect Foundayo · left barVital Harmony Rx · right bar

The numbers

MetricLillyDirect FoundayoVital Harmony Rx
WeighScore67.2/10051.7/100
GradeCC
Scorecard rank#165#484
SemaglutideNot disclosedNot disclosed
TirzepatideNot disclosedNot disclosed
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
LillyDirect Foundayo

Graded #165 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow
Vital Harmony Rx

Graded #484 · C

Strengths

  • Verified LegitScript certification (ID 49230211) — a trust signal many compounded-GLP-1 DTC brands lack
  • Explicit compounded-medication + 'not a pharmacy/manufacturer' disclosure on-site
  • Both a semaglutide (GLP-1+B12) and a tirzepatide (GLP-1/GIP+B12) option
  • Operates on a named physician network (Beluga Health)

Where it loses points

  • NO pricing published anywhere on the site — a major gap for a cost-comparison directory; buyers cannot evaluate value without contacting the company
  • No specific state list (only 'entire country' claimed)
  • No named compounding pharmacy partner
  • No named medical director / PIC, no legal entity or governing law disclosed
  • Molecule strengths/dose tiers not published

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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