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Head-to-head · WeighScore

LillyDirect Foundayo vs Transparent Meds

LillyDirect Foundayo
Graded #173

Higher grade

vs+5.300000000000004
Transparent Meds
Graded #284

Lower grade

The verdict

LillyDirect Foundayo takes it — 67.2/100 to 61.9/100.

LillyDirect Foundayo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Eli Lilly's manufacturer direct-pay channel for Foundayo (orforglipron), the first oral GLP-1 pill for weight loss.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLillyDirect Foundayo +29
72
43
Dose & formulationTransparent Meds +18
59
77
Clinical oversightTransparent Meds +1
78
79
Labs & monitoringEven
52
52
FulfillmentLillyDirect Foundayo +6
80
74
Contract termsLillyDirect Foundayo +14
55
41
LillyDirect Foundayo · left barTransparent Meds · right bar

The numbers

MetricLillyDirect FoundayoTransparent Meds
WeighScore67.2/10061.9/100
GradeCC
Scorecard rank#173#284
SemaglutideNot disclosed$229/mo (promotional rate, compounded)
TirzepatideNot disclosed$349/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesYes
Oral / sublingualYesInjection only
LillyDirect Foundayo

Graded #173 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow
Transparent Meds

Graded #284 · C

Strengths

  • Transparent, upfront monthly pricing — intro $149/mo for compounded semaglutide and $249/mo for tirzepatide (regular $229 / $349)
  • Clean, modern telehealth experience with a quick eligibility quiz and clinician review before any prescription
  • HIPAA-compliant and displays a LegitScript-style verification seal

Where it loses points

  • Headline prices are intro first-month fees — the regular monthly cost is higher ($229 semaglutide, $349 tirzepatide)
  • Connector model that pairs you with licensed providers; it doesn't name its compounding pharmacy
  • Doesn't publish the states it serves, so confirm availability before signing up
  • Compounded semaglutide and tirzepatide injections only — no oral, brand-name, or insurance options

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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