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Head-to-head · WeighScore

LillyDirect Foundayo vs Silhouette MD

LillyDirect Foundayo
Graded #165

Lower grade

vs+2.200000000000003
Silhouette MD
Graded #123

Higher grade

The verdict

Silhouette MD takes it — 69.4/100 to 67.2/100.

Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSilhouette MD +2
72
74
Dose & formulationSilhouette MD +16
59
75
Clinical oversightLillyDirect Foundayo +1
78
77
Labs & monitoringSilhouette MD +2
52
54
FulfillmentLillyDirect Foundayo +13
80
67
Contract termsEven
55
55
LillyDirect Foundayo · left barSilhouette MD · right bar

The numbers

MetricLillyDirect FoundayoSilhouette MD
WeighScore67.2/10069.4/100
GradeCC
Scorecard rank#165#123
SemaglutideNot disclosed$149/mo (compounded)
TirzepatideNot disclosed$299/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesYes
LillyDirect Foundayo

Graded #165 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow
Silhouette MD

Graded #123 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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