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Head-to-head · WeighScore

LillyDirect Foundayo vs Prime Health

LillyDirect Foundayo
Graded #173

Higher grade

vs+7.800000000000004
Prime Health
Graded #344

Lower grade

The verdict

LillyDirect Foundayo takes it — 67.2/100 to 59.4/100.

LillyDirect Foundayo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Eli Lilly's manufacturer direct-pay channel for Foundayo (orforglipron), the first oral GLP-1 pill for weight loss.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLillyDirect Foundayo +30
72
42
Dose & formulationPrime Health +5
59
64
Clinical oversightLillyDirect Foundayo +4
78
74
Labs & monitoringPrime Health +13
52
65
FulfillmentLillyDirect Foundayo +11
80
69
Contract termsLillyDirect Foundayo +14
55
41
LillyDirect Foundayo · left barPrime Health · right bar

The numbers

MetricLillyDirect FoundayoPrime Health
WeighScore67.2/10059.4/100
GradeCC
Scorecard rank#173#344
SemaglutideNot disclosed$299/mo (compounded)
TirzepatideNot disclosed$399/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
LillyDirect Foundayo

Graded #173 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow
Prime Health

Graded #344 · C

Strengths

  • LegitScript-certified platform
  • Flat pricing that does not rise as dosage increases
  • Bundle includes medication, labs, shipping, and unlimited clinician access
  • Money-back guarantee of at least 10% body-weight loss in 4 months
  • Fast 24-hour prescription review and 5-7 day delivery

Where it loses points

  • Compounded medications only; no FDA-approved brand options listed
  • Not available in Louisiana
  • Care delivered through third-party clinician groups, not in-house
  • Named compounding pharmacy not disclosed
  • No insurance accepted

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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