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Head-to-head · WeighScore

LillyDirect Foundayo vs Piper

LillyDirect Foundayo
Graded #165

Lower grade

vs+14.700000000000003
Piper
Graded #34

Higher grade

The verdict

Piper takes it — 81.9/100 to 67.2/100.

Piper grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Mid-value both-molecule pricing ($135/$199), nationwide, though not verified.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePiper +14
72
86
Dose & formulationPiper +21
59
80
Clinical oversightPiper +1
78
79
Labs & monitoringPiper +26
52
78
FulfillmentPiper +6
80
86
Contract termsPiper +27
55
82
LillyDirect Foundayo · left barPiper · right bar

The numbers

MetricLillyDirect FoundayoPiper
WeighScore67.2/10081.9/100
GradeCB−
Scorecard rank#165#34
SemaglutideNot disclosed$135/mo
TirzepatideNot disclosed$199/mo
CoverageAll 50 statesAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
LillyDirect Foundayo

Graded #165 · C

Strengths

  • Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
  • Direct from manufacturer — no compounding, no third-party reseller
  • Daily oral pill, no injections, no refrigeration
  • Available in all 50 states

Where it loses points

  • Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
  • Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
  • $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
  • Strict empty-stomach 30-minute window may be hard for some patients to follow
Piper

Graded #34 · B−

Strengths

  • $135 sema / $199 tirz
  • All 50 states
  • Both molecules

Where it loses points

  • Not LegitScript-verified
  • Injection-only
  • Monitoring detail limited

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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