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Head-to-head · WeighScore

LifespanningRx vs SkyRx

LifespanningRx
Graded #322

Higher grade

vs+1.5
SkyRx
Graded #355

Lower grade

The verdict

LifespanningRx takes it — 60.4/100 to 58.9/100, but only just.

LifespanningRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LifespanningRx is a clinician-guided longevity and peptide telehealth brand whose Weight Loss Program prescribes compounded GLP-1 (semaglutide/tirzepatide) injectables alongside peptide and healthy-aging… SkyRx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSkyRx +11
45
56
Dose & formulationSkyRx +18
53
71
Clinical oversightLifespanningRx +13
81
68
Labs & monitoringLifespanningRx +1
53
52
FulfillmentLifespanningRx +19
83
64
Contract termsLifespanningRx +35
55
20
LifespanningRx · left barSkyRx · right bar

The numbers

MetricLifespanningRxSkyRx
WeighScore60.4/10058.9/100
GradeCC
Scorecard rank#322#355
SemaglutideNot disclosed$199/mo (all doses, 12-month plan, compounded)
TirzepatideNot disclosedNot disclosed
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyYes
LifespanningRx

Graded #322 · C

Strengths

  • Compounded GLP-1 (semaglutide/tirzepatide) weight-loss program with licensed clinicians included
  • LegitScript-certified and HIPAA-compliant; works with 503A/503B licensed US pharmacies
  • Longevity and peptide protocols alongside weight loss; free membership, no monthly fee
  • Discreet nationwide shipping with 24/365 support
  • Also a turnkey white-label platform for clinics and wellness brands to launch programs

Where it loses points

  • Exact dosing and pricing are shown only after completing the patient assessment
  • Compounded GLP-1s are not FDA-approved finished products
  • States served are not publicly listed
  • Part B2B/white-label, so the consumer experience can vary by partnered clinic
SkyRx

Graded #355 · C

Strengths

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Where it loses points

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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