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Head-to-head · WeighScore

LifespanningRx vs Open Water Rx

LifespanningRx
Graded #324

Higher grade

vs+1.6000000000000014
Open Water Rx
Graded #359

Lower grade

The verdict

LifespanningRx takes it — 60.4/100 to 58.8/100, but only just.

LifespanningRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LifespanningRx is a clinician-guided longevity and peptide telehealth brand whose Weight Loss Program prescribes compounded GLP-1 (semaglutide/tirzepatide) injectables alongside peptide and healthy-aging… Open Water Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueOpen Water Rx +3
45
48
Dose & formulationOpen Water Rx +35
53
88
Clinical oversightLifespanningRx +27
81
54
Labs & monitoringOpen Water Rx +7
53
60
FulfillmentLifespanningRx +41
83
42
Contract termsEven
55
55
LifespanningRx · left barOpen Water Rx · right bar

The numbers

MetricLifespanningRxOpen Water Rx
WeighScore60.4/10058.8/100
GradeCC
Scorecard rank#324#359
SemaglutideNot disclosed$249/mo (compounded)
TirzepatideNot disclosed$339/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesYes
Oral / sublingualInjection onlyYes
LifespanningRx

Graded #324 · C

Strengths

  • Compounded GLP-1 (semaglutide/tirzepatide) weight-loss program with licensed clinicians included
  • LegitScript-certified and HIPAA-compliant; works with 503A/503B licensed US pharmacies
  • Longevity and peptide protocols alongside weight loss; free membership, no monthly fee
  • Discreet nationwide shipping with 24/365 support
  • Also a turnkey white-label platform for clinics and wellness brands to launch programs

Where it loses points

  • Exact dosing and pricing are shown only after completing the patient assessment
  • Compounded GLP-1s are not FDA-approved finished products
  • States served are not publicly listed
  • Part B2B/white-label, so the consumer experience can vary by partnered clinic
Open Water Rx

Graded #359 · C

Strengths

  • Combines weight-loss and longevity verticals in one brand
  • Established brand domain

Where it loses points

  • Limited public data — most details are gated behind signup or rendered only in JavaScript
  • Pricing not disclosed
  • GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
  • States-served list not disclosed
  • Pharmacy partner not named

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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