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Head-to-head · WeighScore

LifespanningRx vs Lyfe Rx

LifespanningRx
Graded #322

Higher grade

vs+2.1000000000000014
Lyfe Rx
Graded #375

Lower grade

The verdict

LifespanningRx takes it — 60.4/100 to 58.3/100.

LifespanningRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LifespanningRx is a clinician-guided longevity and peptide telehealth brand whose Weight Loss Program prescribes compounded GLP-1 (semaglutide/tirzepatide) injectables alongside peptide and healthy-aging…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLyfe Rx +5
45
50
Dose & formulationLyfe Rx +11
53
64
Clinical oversightLifespanningRx +14
81
67
Labs & monitoringLifespanningRx +1
53
52
FulfillmentLifespanningRx +21
83
62
Contract termsEven
55
55
LifespanningRx · left barLyfe Rx · right bar

The numbers

MetricLifespanningRxLyfe Rx
WeighScore60.4/10058.3/100
GradeCC
Scorecard rank#322#375
SemaglutideNot disclosed$225/mo (compounded)
TirzepatideNot disclosed$299/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
LifespanningRx

Graded #322 · C

Strengths

  • Compounded GLP-1 (semaglutide/tirzepatide) weight-loss program with licensed clinicians included
  • LegitScript-certified and HIPAA-compliant; works with 503A/503B licensed US pharmacies
  • Longevity and peptide protocols alongside weight loss; free membership, no monthly fee
  • Discreet nationwide shipping with 24/365 support
  • Also a turnkey white-label platform for clinics and wellness brands to launch programs

Where it loses points

  • Exact dosing and pricing are shown only after completing the patient assessment
  • Compounded GLP-1s are not FDA-approved finished products
  • States served are not publicly listed
  • Part B2B/white-label, so the consumer experience can vary by partnered clinic
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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