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Head-to-head · WeighScore

LifeRx.md vs Silhouette MD

LifeRx.md
Graded #127

Lower grade

vs+0.10000000000000853
Silhouette MD
Graded #123

Higher grade

The verdict

Silhouette MD takes it — 69.4/100 to 69.3/100, but only just.

Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan. LifeRx.md is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSilhouette MD +17
57
74
Dose & formulationSilhouette MD +3
72
75
Clinical oversightLifeRx.md +9
86
77
Labs & monitoringLifeRx.md +8
62
54
FulfillmentLifeRx.md +14
81
67
Contract termsEven
55
55
LifeRx.md · left barSilhouette MD · right bar

The numbers

MetricLifeRx.mdSilhouette MD
WeighScore69.3/10069.4/100
GradeCC
Scorecard rank#127#123
Semaglutide$200/mo$149/mo (compounded)
Tirzepatide$275/mo$299/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
LifeRx.md

Graded #127 · C

Strengths

  • Flat pricing that does not rise with dose: semaglutide ~$200, tirzepatide ~$275 per 5-week supply
  • LegitScript certified; prescriptions filled by state-licensed 503A pharmacies
  • Available in all 50 states
  • HSA and FSA payments accepted
  • Required video telehealth consult ensures clinician oversight

Where it loses points

  • Compounded GLP-1s are not FDA-approved for safety, efficacy or quality
  • Extra fees stack up: ~$30 shipping, $49.95 initial consult, $25 follow-ups
  • True monthly cost (~$255) is higher than the headline medication price
  • Specific list of supported states not enumerated on site
Silhouette MD

Graded #123 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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