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Head-to-head · WeighScore

LevelUp Rx vs PCOS Sisters

LevelUp Rx
Graded #239

Lower grade

vs+1.5999999999999943
PCOS Sisters
Graded #211

Higher grade

The verdict

PCOS Sisters takes it — 66/100 to 64.4/100, but only just.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required. LevelUp Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +4
58
62
Dose & formulationPCOS Sisters +24
64
88
Clinical oversightLevelUp Rx +14
84
70
Labs & monitoringLevelUp Rx +1
53
52
FulfillmentLevelUp Rx +11
76
65
Contract termsEven
41
41
LevelUp Rx · left barPCOS Sisters · right bar

The numbers

MetricLevelUp RxPCOS Sisters
WeighScore64.4/10066/100
GradeCC
Scorecard rank#239#211
Semaglutide$150/mo (starting dose, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$250/mo (starting dose, compounded)$150/mo (plus a separate fee, compounded)
CoverageCoverage not published12 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
LevelUp Rx

Graded #239 · C

Strengths

  • Compounded semaglutide ($149.97/mo) and tirzepatide ($249.97/mo) on one platform
  • Flat monthly price that never changes with your dose
  • No-cost online consultation included with your order
  • LegitScript-certified; partner pharmacies named (DiRx and The DrugStore)
  • Free shipping with no insurance required

Where it loses points

  • Compounded only - no brand-name Wegovy, Zepbound, Ozempic or Mounjaro
  • No single prescribing medical group named; physicians listed only for CA, MA, RI and VT
  • State availability is confirmed during intake, not published as a list
  • Prescription sales are final once shipped; no returns on dispensed medication
PCOS Sisters

Graded #211 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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