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Head-to-head · WeighScore

LevelUp Rx vs Nucific

LevelUp Rx
Graded #246

Higher grade

vs+8
Nucific
Graded #417

Lower grade

The verdict

LevelUp Rx takes it — 64.2/100 to 56.2/100.

LevelUp Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LevelUp Rx is a telehealth pharmacy offering compounded GLP-1 weight-loss medications - compounded semaglutide and compounded tirzepatide - alongside a broad menu of men's and women's health treatments.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLevelUp Rx +12
57
45
Dose & formulationLevelUp Rx +11
64
53
Clinical oversightLevelUp Rx +8
84
76
Labs & monitoringLevelUp Rx +1
53
52
FulfillmentLevelUp Rx +9
76
67
Contract termsEven
41
41
LevelUp Rx · left barNucific · right bar

The numbers

MetricLevelUp RxNucific
WeighScore64.2/10056.2/100
GradeCC
Scorecard rank#246#417
Semaglutide$150/mo (starting dose, compounded)Not disclosed
Tirzepatide$250/mo (starting dose, compounded)Not disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
LevelUp Rx

Graded #246 · C

Strengths

  • Compounded semaglutide ($149.97/mo) and tirzepatide ($249.97/mo) on one platform
  • Flat monthly price that never changes with your dose
  • No-cost online consultation included with your order
  • LegitScript-certified; partner pharmacies named (DiRx and The DrugStore)
  • Free shipping with no insurance required

Where it loses points

  • Compounded only - no brand-name Wegovy, Zepbound, Ozempic or Mounjaro
  • No single prescribing medical group named; physicians listed only for CA, MA, RI and VT
  • State availability is confirmed during intake, not published as a list
  • Prescription sales are final once shipped; no returns on dispensed medication
Nucific

Graded #417 · C

Strengths

  • Founder is named and credentialed: Dr. Amy Lee, MD, triple board-certified in Internal Medicine, Obesity Medicine and Clinical Nutrition
  • Cites SURMOUNT-1 properly, naming the trial, the 20.9% average and the Jastreboff NEJM 2022 source
  • Discloses that featured patients were compensated for their time
  • Labels its NAD+ decline chart as illustrative and not a measurement, with an unusually careful methodology note
  • Offers compounded, microdosed and brand-name Ozempic and Zepbound in one catalogue

Where it loses points

  • No price is published anywhere; every option is gated behind a three-minute quiz
  • The LegitScript badge is a self-hosted image with generic alt text rather than the issued embed, so the certification could not be verified
  • A BBB Accredited A+ claim is displayed without a link to the BBB profile
  • No state list and no named pharmacy, only licensed U.S. pharmacies
  • Before-and-after photographs are used alongside compensated testimonials

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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