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Head-to-head · WeighScore

LevelUp Rx vs Lyfe Rx

LevelUp Rx
Graded #246

Higher grade

vs+5.900000000000006
Lyfe Rx
Graded #375

Lower grade

The verdict

LevelUp Rx takes it — 64.2/100 to 58.3/100.

LevelUp Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LevelUp Rx is a telehealth pharmacy offering compounded GLP-1 weight-loss medications - compounded semaglutide and compounded tirzepatide - alongside a broad menu of men's and women's health treatments.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLevelUp Rx +7
57
50
Dose & formulationEven
64
64
Clinical oversightLevelUp Rx +17
84
67
Labs & monitoringLevelUp Rx +1
53
52
FulfillmentLevelUp Rx +14
76
62
Contract termsLyfe Rx +14
41
55
LevelUp Rx · left barLyfe Rx · right bar

The numbers

MetricLevelUp RxLyfe Rx
WeighScore64.2/10058.3/100
GradeCC
Scorecard rank#246#375
Semaglutide$150/mo (starting dose, compounded)$225/mo (compounded)
Tirzepatide$250/mo (starting dose, compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
LevelUp Rx

Graded #246 · C

Strengths

  • Compounded semaglutide ($149.97/mo) and tirzepatide ($249.97/mo) on one platform
  • Flat monthly price that never changes with your dose
  • No-cost online consultation included with your order
  • LegitScript-certified; partner pharmacies named (DiRx and The DrugStore)
  • Free shipping with no insurance required

Where it loses points

  • Compounded only - no brand-name Wegovy, Zepbound, Ozempic or Mounjaro
  • No single prescribing medical group named; physicians listed only for CA, MA, RI and VT
  • State availability is confirmed during intake, not published as a list
  • Prescription sales are final once shipped; no returns on dispensed medication
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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