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Head-to-head · WeighScore

LeanDose vs PlexusDx

LeanDose
Graded #184

Lower grade

vs+0.9000000000000057
PlexusDx
Graded #162

Higher grade

The verdict

PlexusDx takes it — 67.7/100 to 66.8/100, but only just.

PlexusDx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states. LeanDose is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePlexusDx +9
65
74
Dose & formulationEven
64
64
Clinical oversightLeanDose +5
79
74
Labs & monitoringLeanDose +2
54
52
FulfillmentLeanDose +1
79
78
Contract termsEven
55
55
LeanDose · left barPlexusDx · right bar

The numbers

MetricLeanDosePlexusDx
WeighScore66.8/10067.7/100
GradeCC
Scorecard rank#184#162
Semaglutide$159/mo (first-month rate, compounded)$149/mo (starting dose, compounded)
Tirzepatide$279/mo (first-month rate, compounded)$249/mo (starting dose, compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
LeanDose

Graded #184 · C

Strengths

  • Transparent all-inclusive first-month pricing (compounded semaglutide from $159, tirzepatide from $279)
  • Verifiable LegitScript certification (seal ID 49840868) and an FDA-registered compounding pharmacy
  • Doctor-prescribed and supervised, with personalized care plans and multi-state clinical support
  • Convenient at-home delivery; compounded semaglutide and tirzepatide options
  • Honest, modest social proof — 119 five-star patient reviews

Where it loses points

  • Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
  • Headline rates are first-month pricing; your ongoing monthly cost may be higher
  • Available in multiple states but the full list is not published on the homepage
  • The compounding pharmacy is FDA-registered but not named
PlexusDx

Graded #162 · C

Strengths

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Where it loses points

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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