Head-to-head · WeighScore
Lean Rx vs SynergenX Health
The verdict
Lean Rx takes it — 60.6/100 to 58.1/100.
Lean Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Lean Rx is a Sacramento-based telehealth technology platform offering compounded GLP-1 weight loss medications.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lean Rx | SynergenX Health |
|---|---|---|
| WeighScore | 60.6/100 | 58.1/100 |
| Grade | C | C |
| Scorecard rank | #319 | #380 |
| Semaglutide | $266/mo (starting dose, compounded) | $150/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide | $399/mo (starting dose, compounded) | Not disclosed |
| Coverage | Coverage not published | 10 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #319 · C
Strengths
- Both semaglutide and tirzepatide offered
- Three formulations: injectable, sublingual, and tablet
- Upfront pricing with no hidden fees advertised
- Semaglutide starts at a low $266/month
- Telehealth call with a licensed provider before prescribing
Where it loses points
- Compounded-only; no FDA-approved branded options
- No published state availability list
- Platform is technology only, not a healthcare provider itself
- Provider credentials not detailed on site
Graded #380 · C
Strengths
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Where it loses points
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.