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Head-to-head · WeighScore

Lean Rx vs PCOS Sisters

Lean Rx
Graded #319

Lower grade

vs+5.100000000000001
PCOS Sisters
Graded #219

Higher grade

The verdict

PCOS Sisters takes it — 65.7/100 to 60.6/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +21
40
61
Dose & formulationPCOS Sisters +13
75
88
Clinical oversightLean Rx +11
81
70
Labs & monitoringEven
52
52
FulfillmentPCOS Sisters +5
60
65
Contract termsLean Rx +14
55
41
Lean Rx · left barPCOS Sisters · right bar

The numbers

MetricLean RxPCOS Sisters
WeighScore60.6/10065.7/100
GradeCC
Scorecard rank#319#219
Semaglutide$266/mo (starting dose, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$399/mo (starting dose, compounded)$150/mo (plus a separate fee, compounded)
CoverageCoverage not published12 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
Lean Rx

Graded #319 · C

Strengths

  • Both semaglutide and tirzepatide offered
  • Three formulations: injectable, sublingual, and tablet
  • Upfront pricing with no hidden fees advertised
  • Semaglutide starts at a low $266/month
  • Telehealth call with a licensed provider before prescribing

Where it loses points

  • Compounded-only; no FDA-approved branded options
  • No published state availability list
  • Platform is technology only, not a healthcare provider itself
  • Provider credentials not detailed on site
PCOS Sisters

Graded #219 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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