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Head-to-head · WeighScore

Lean Rx vs Lyfe Rx

Lean Rx
Graded #319

Higher grade

vs+2.3000000000000043
Lyfe Rx
Graded #375

Lower grade

The verdict

Lean Rx takes it — 60.6/100 to 58.3/100.

Lean Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Lean Rx is a Sacramento-based telehealth technology platform offering compounded GLP-1 weight loss medications.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLyfe Rx +10
40
50
Dose & formulationLean Rx +11
75
64
Clinical oversightLean Rx +14
81
67
Labs & monitoringEven
52
52
FulfillmentLyfe Rx +2
60
62
Contract termsEven
55
55
Lean Rx · left barLyfe Rx · right bar

The numbers

MetricLean RxLyfe Rx
WeighScore60.6/10058.3/100
GradeCC
Scorecard rank#319#375
Semaglutide$266/mo (starting dose, compounded)$225/mo (compounded)
Tirzepatide$399/mo (starting dose, compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Lean Rx

Graded #319 · C

Strengths

  • Both semaglutide and tirzepatide offered
  • Three formulations: injectable, sublingual, and tablet
  • Upfront pricing with no hidden fees advertised
  • Semaglutide starts at a low $266/month
  • Telehealth call with a licensed provider before prescribing

Where it loses points

  • Compounded-only; no FDA-approved branded options
  • No published state availability list
  • Platform is technology only, not a healthcare provider itself
  • Provider credentials not detailed on site
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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