Head-to-head · WeighScore
Layla vs Rex MD
The verdict
Layla takes it — 70.9/100 to 70.2/100, but only just.
Layla grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Layla is a US telehealth weight-loss program built around semaglutide, offering compounded semaglutide as injections and as oral dropper drops, plus compounded tirzepatide and a brand-inclusive GLP-1… Rex MD is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Layla | Rex MD |
|---|---|---|
| WeighScore | 70.9/100 | 70.2/100 |
| Grade | C | C |
| Scorecard rank | #103 | #109 |
| Semaglutide | $237/mo (all doses, compounded) | $199/mo (brand-name) |
| Tirzepatide | $199/mo (all doses, compounded) | $349/mo (brand Zepbound) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #103 · C
Strengths
- Oral semaglutide dropper option plus injectable semaglutide and tirzepatide, with a brand-name upgrade path
- Named Medical Director (Dr. Ruth Cohen) and 24-7 doctor messaging
- Quiz-based intake with fast three to five day shipping
Where it loses points
- Brand-inclusive GLP-1 program is expensive, starting around 1,299 dollars
- States served are not published on the site
- Support phone line uses a UK format, and the compounding pharmacy is not named
Graded #109 · C
Strengths
- Flat $199/mo program bundles consult, medication and overnight shipping
- Brand-name semaglutide and Zepbound vials, not just compounded
- Serves all 50 states, fully online
- LegitScript certified with US-based, state-licensed providers
- Backed by parent company LifeMD
Where it loses points
- Does not accept insurance
- Marketed primarily to men via a men's-health platform
- Zepbound vial cost rises with dose titration
- Branded-only program costs more than compounded options
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.