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Head-to-head · WeighScore

Layla vs Onyx Weight Loss

Layla
Graded #101

Higher grade

vs+12.100000000000009
Onyx Weight Loss
Graded #359

Lower grade

The verdict

Layla takes it — 70.9/100 to 58.8/100.

Layla grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Layla is a US telehealth weight-loss program built around semaglutide, offering compounded semaglutide as injections and as oral dropper drops, plus compounded tirzepatide and a brand-inclusive GLP-1…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLayla +23
66
43
Dose & formulationLayla +32
96
64
Clinical oversightLayla +1
76
75
Labs & monitoringOnyx Weight Loss +11
52
63
FulfillmentLayla +12
65
53
Contract termsEven
55
55
Layla · left barOnyx Weight Loss · right bar

The numbers

MetricLaylaOnyx Weight Loss
WeighScore70.9/10058.8/100
GradeCC
Scorecard rank#101#359
Semaglutide$237/mo (all doses, compounded)$228/mo (starting dose, compounded)
Tirzepatide$199/mo (all doses, compounded)$280/mo (starting dose, compounded)
CoverageCoverage not published8 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
Layla

Graded #101 · C

Strengths

  • Oral semaglutide dropper option plus injectable semaglutide and tirzepatide, with a brand-name upgrade path
  • Named Medical Director (Dr. Ruth Cohen) and 24-7 doctor messaging
  • Quiz-based intake with fast three to five day shipping

Where it loses points

  • Brand-inclusive GLP-1 program is expensive, starting around 1,299 dollars
  • States served are not published on the site
  • Support phone line uses a UK format, and the compounding pharmacy is not named
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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