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Head-to-head · WeighScore

Knownwell vs Vytora Health

Knownwell
Graded #172

Lower grade

vs+5.3999999999999915
Vytora Health
Graded #79

Higher grade

The verdict

Vytora Health takes it — 72.3/100 to 66.9/100.

Vytora Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueVytora Health +21
38
59
Dose & formulationVytora Health +9
76
85
Clinical oversightVytora Health +6
90
96
Labs & monitoringKnownwell +8
63
55
FulfillmentVytora Health +10
86
96
Contract termsKnownwell +35
55
20
Knownwell · left barVytora Health · right bar

The numbers

MetricKnownwellVytora Health
WeighScore66.9/10072.3/100
GradeCC
Scorecard rank#172#79
SemaglutideNot disclosed$180/mo (all doses, compounded)
Tirzepatide$349/mo (brand Zepbound)$249/mo (all doses, compounded)
CoverageAll 50 statesAll 50 states
Brand-name accessYesYes
Oral / sublingualYesInjection only
Knownwell

Graded #172 · C

Strengths

  • Co-founded by obesity-medicine specialist Dr. Angela Fitch
  • Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
  • Official LillyDirect provider and Novo Wegovy-pill telehealth partner
  • Accepts insurance, copays as low as $25 for covered patients
  • Weight-inclusive care with dietitians and health coaches

Where it loses points

  • Specific self-pay monthly medication prices not transparently posted
  • In-person clinics limited to four metro areas
  • Branded-only focus can mean higher cost than compounded routes
Vytora Health

Graded #79 · C

Strengths

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)

Where it loses points

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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