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Head-to-head · WeighScore

Knownwell vs PCOS Sisters

Knownwell
Graded #172

Higher grade

vs+0.9000000000000057
PCOS Sisters
Graded #211

Lower grade

The verdict

Knownwell takes it — 66.9/100 to 66/100, but only just.

Knownwell grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Knownwell is a weight-inclusive metabolic and primary care company co-founded by obesity-medicine specialist Dr. PCOS Sisters is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +24
38
62
Dose & formulationPCOS Sisters +12
76
88
Clinical oversightKnownwell +20
90
70
Labs & monitoringKnownwell +11
63
52
FulfillmentKnownwell +21
86
65
Contract termsKnownwell +14
55
41
Knownwell · left barPCOS Sisters · right bar

The numbers

MetricKnownwellPCOS Sisters
WeighScore66.9/10066/100
GradeCC
Scorecard rank#172#211
SemaglutideNot disclosed$150/mo (plus a separate fee, compounded)
Tirzepatide$349/mo (brand Zepbound)$150/mo (plus a separate fee, compounded)
CoverageAll 50 states12 states
Brand-name accessYesYes
Oral / sublingualYesYes
Knownwell

Graded #172 · C

Strengths

  • Co-founded by obesity-medicine specialist Dr. Angela Fitch
  • Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
  • Official LillyDirect provider and Novo Wegovy-pill telehealth partner
  • Accepts insurance, copays as low as $25 for covered patients
  • Weight-inclusive care with dietitians and health coaches

Where it loses points

  • Specific self-pay monthly medication prices not transparently posted
  • In-person clinics limited to four metro areas
  • Branded-only focus can mean higher cost than compounded routes
PCOS Sisters

Graded #211 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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