Head-to-head · WeighScore
Knownwell vs Optimized Health
The verdict
Optimized Health takes it — 67.2/100 to 66.9/100, but only just.
Optimized Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Optimized Health is a concierge medical weight loss and hormone clinic offering clinician-supervised GLP-1 programs with compounded semaglutide and tirzepatide, plus oral options like phentermine. Knownwell is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Knownwell | Optimized Health |
|---|---|---|
| WeighScore | 66.9/100 | 67.2/100 |
| Grade | C | C |
| Scorecard rank | #172 | #166 |
| Semaglutide | Not disclosed | $200/mo (starting dose, compounded) |
| Tirzepatide | $349/mo (brand Zepbound) | $250/mo (starting dose, compounded) |
| Coverage | All 50 states | 5 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #172 · C
Strengths
- Co-founded by obesity-medicine specialist Dr. Angela Fitch
- Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
- Official LillyDirect provider and Novo Wegovy-pill telehealth partner
- Accepts insurance, copays as low as $25 for covered patients
- Weight-inclusive care with dietitians and health coaches
Where it loses points
- Specific self-pay monthly medication prices not transparently posted
- In-person clinics limited to four metro areas
- Branded-only focus can mean higher cost than compounded routes
Graded #166 · C
Strengths
- Fully transparent pricing published on the website
- Semaglutide from $200/mo and tirzepatide from $250/mo
- Lab panels included with clinician-supervised dosing
- LegitScript certified clinic
- Lead PA-C with over a decade in obesity medicine
Where it loses points
- Telehealth limited to MO, IA, KS, UT, and WA
- Compounded GLP-1 only, not brand-name
- No insurance billing (cash-pay)
- PA-led rather than MD/DO-led
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.