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Head-to-head · WeighScore

Knownwell vs MyStart Health

Knownwell
Graded #172

Lower grade

vs+0.19999999999998863
MyStart Health
Graded #168

Higher grade

The verdict

MyStart Health takes it — 67.1/100 to 66.9/100, but only just.

MyStart Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access. Knownwell is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueMyStart Health +10
38
48
Dose & formulationMyStart Health +7
76
83
Clinical oversightKnownwell +6
90
84
Labs & monitoringMyStart Health +3
63
66
FulfillmentKnownwell +8
86
78
Contract termsKnownwell +24
55
31
Knownwell · left barMyStart Health · right bar

The numbers

MetricKnownwellMyStart Health
WeighScore66.9/10067.1/100
GradeCC
Scorecard rank#172#168
SemaglutideNot disclosed$299/mo (all doses, compounded)
Tirzepatide$349/mo (brand Zepbound)$299/mo (all doses, compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesYes
Knownwell

Graded #172 · C

Strengths

  • Co-founded by obesity-medicine specialist Dr. Angela Fitch
  • Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
  • Official LillyDirect provider and Novo Wegovy-pill telehealth partner
  • Accepts insurance, copays as low as $25 for covered patients
  • Weight-inclusive care with dietitians and health coaches

Where it loses points

  • Specific self-pay monthly medication prices not transparently posted
  • In-person clinics limited to four metro areas
  • Branded-only focus can mean higher cost than compounded routes
MyStart Health

Graded #168 · C

Strengths

  • Price Lock Guarantee — your $299 base rate doesn't rise as your dose escalates
  • Fast onboarding: roughly 5-minute intake, 24-hour prescription turnaround, 2–4 day shipping
  • 24/7 care team access with unlimited clinician messaging included
  • LegitScript certified
  • Clear Section 503A compounding disclosure on every landing page

Where it loses points

  • Not BBB accredited — C+ rating with 10 complaints, mostly shipping delays and support access
  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Markets oral tirzepatide, but no FDA-approved oral tirzepatide exists
  • Very new company (incorporated May 2024) with a limited track record
  • Pharmacy partners not named, so 503A compliance can't be independently verified

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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