Head-to-head · WeighScore
Jyra Health vs PCOS Sisters
The verdict
Jyra Health takes it — 69.6/100 to 66/100.
Jyra Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Jyra Health | PCOS Sisters |
|---|---|---|
| WeighScore | 69.6/100 | 66/100 |
| Grade | C | C |
| Scorecard rank | #117 | #211 |
| Semaglutide | $99/mo (starting dose, plus a separate fee, compounded) | $150/mo (plus a separate fee, compounded) |
| Tirzepatide | $133/mo (starting dose, promotional rate, compounded) | $150/mo (plus a separate fee, compounded) |
| Coverage | All 50 states | 12 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #117 · C
Strengths
- Among the lowest compounded pricing — semaglutide from $99/mo and tirzepatide from $133/mo, with no membership and no hidden fees
- Board-certified providers in all 50 states; no insurance required and free express delivery
- Offers both compounded semaglutide and tirzepatide, plus a longevity track
- Full legal suite published (Privacy, Terms, HIPAA, Refunds & Cancellations)
Where it loses points
- The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
- Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Zepbound, Ozempic, or Mounjaro
- Displays a self-hosted LegitScript badge but no verifiable seal or listing
- Compounding pharmacy not named; appears to be a newer, smaller clinic (~300 patients/month)
Graded #211 · C
Strengths
- Dedicated PCOS specialty model with metabolic program and fitness app included
- Transparent 150 dollars per month GLP-1 management fee
- Names real partner pharmacies (Strive, Striker) and lists phone support
Where it loses points
- Only 12 states served
- Membership required on top of the medical program
- Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.