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Head-to-head · WeighScore

Jyra Health vs MD Trim Clinic

Jyra Health
Graded #117

Higher grade

vs+13.499999999999993
MD Trim Clinic
Graded #421

Lower grade

The verdict

Jyra Health takes it — 69.6/100 to 56.1/100.

Jyra Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueJyra Health +27
72
45
Dose & formulationJyra Health +24
64
40
Clinical oversightJyra Health +2
82
80
Labs & monitoringMD Trim Clinic +10
53
63
FulfillmentJyra Health +30
88
58
Contract termsMD Trim Clinic +6
49
55
Jyra Health · left barMD Trim Clinic · right bar

The numbers

MetricJyra HealthMD Trim Clinic
WeighScore69.6/10056.1/100
GradeCC
Scorecard rank#117#421
Semaglutide$99/mo (starting dose, plus a separate fee, compounded)Not disclosed
Tirzepatide$133/mo (starting dose, promotional rate, compounded)Not disclosed
CoverageAll 50 states2 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Jyra Health

Graded #117 · C

Strengths

  • Among the lowest compounded pricing — semaglutide from $99/mo and tirzepatide from $133/mo, with no membership and no hidden fees
  • Board-certified providers in all 50 states; no insurance required and free express delivery
  • Offers both compounded semaglutide and tirzepatide, plus a longevity track
  • Full legal suite published (Privacy, Terms, HIPAA, Refunds & Cancellations)

Where it loses points

  • The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
  • Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Zepbound, Ozempic, or Mounjaro
  • Displays a self-hosted LegitScript badge but no verifiable seal or listing
  • Compounding pharmacy not named; appears to be a newer, smaller clinic (~300 patients/month)
MD Trim Clinic

Graded #421 · C

Strengths

  • Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
  • Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
  • Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
  • Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
  • Partnered mobile IV services available for enhanced nausea management and hydration support

Where it loses points

  • Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
  • Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
  • No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
  • Small practice with limited online presence and no published patient reviews or outcomes data
  • No labs, coaching, or monitoring protocols disclosed on the site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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