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Head-to-head · WeighScore

Joi + Blokes vs SynergenX Health

Joi + Blokes
Graded #203

Higher grade

vs+7.699999999999996
SynergenX Health
Graded #374

Lower grade

The verdict

Joi + Blokes takes it — 66.1/100 to 58.4/100.

Joi + Blokes grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Joi + Blokes is a hormone-first telehealth platform with parallel programs for women (Joi) and men (Blokes), now expanded to compounded GLP-1s for weight loss.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueJoi + Blokes +4
50
46
Dose & formulationJoi + Blokes +12
64
52
Clinical oversightJoi + Blokes +20
86
66
Labs & monitoringJoi + Blokes +1
87
86
FulfillmentJoi + Blokes +20
75
55
Contract termsSynergenX Health +27
20
47
Joi + Blokes · left barSynergenX Health · right bar

The numbers

MetricJoi + BlokesSynergenX Health
WeighScore66.1/10058.4/100
GradeCC
Scorecard rank#203#374
Semaglutide$199/mo (promotional rate, quarterly plan, compounded)$150/mo (starting dose, plus a separate fee, compounded)
Tirzepatide$299/mo (quarterly plan, compounded)Not disclosed
CoverageCoverage not published10 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Joi + Blokes

Graded #203 · C

Strengths

  • Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
  • Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
  • Monthly price includes medication, dosing support, clinician consults, and health coaching
  • Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
  • First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s

Where it loses points

  • Billed quarterly — a 3-month commitment up front, not month-to-month
  • Different pricing in NY and NJ — verify your state's cost before committing
  • Per-state availability isn't listed; it's zip-code gated behind signup
  • Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
  • No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
SynergenX Health

Graded #374 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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