Head-to-head · WeighScore
iThriveMD vs Synergy Rx
The verdict
Synergy Rx takes it — 76.2/100 to 66.7/100.
Synergy Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | iThriveMD | Synergy Rx |
|---|---|---|
| WeighScore | 66.7/100 | 76.2/100 |
| Grade | C | C |
| Scorecard rank | #186 | #41 |
| Semaglutide | $299/mo (starting dose, compounded) | From $199/mo |
| Tirzepatide | $399/mo (starting dose, compounded) | From $349/mo |
| Coverage | Coverage not published | Not disclosed |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #186 · C
Strengths
- Compounded semaglutide (from $299/mo) and tirzepatide (from $399/mo), plus microdosing tirzepatide programs
- Lab testing and personalized protocols with a medical team; free initial consultation
- Very thorough legal/policy suite (Terms, Privacy, EUA, Shipping, Returns, CCPA)
- Broad longevity menu: hormones (HRT/TRT), NAD+, peptides, IV therapy, sexual health, diagnostics
Where it loses points
- Premium pricing — higher than budget compounded-GLP-1 competitors (lowest rates need 'preferred pricing')
- Headline GLP-1 pricing is 'starting at'; full cost depends on dose and program length
- Compounding pharmacy partner not named
- Not LegitScript-certified (no certification displayed)
Graded #41 · C
Strengths
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- $100 welcome credit at checkout, and FSA/HSA eligible
Where it loses points
- Publishes no GLP-1 price anywhere on its own site
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
- No published cancellation or refund terms
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.