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Head-to-head · WeighScore

iThriveMD vs PCOS Sisters

iThriveMD
Graded #186

Higher grade

vs+1
PCOS Sisters
Graded #219

Lower grade

The verdict

iThriveMD takes it — 66.7/100 to 65.7/100, but only just.

iThriveMD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. iThriveMD is a longevity and metabolic-health clinic (physical locations plus telehealth) offering compounded GLP-1 weight loss — semaglutide (from $299/mo) and tirzepatide (from $399/mo), plus microdosing… PCOS Sisters is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +25
36
61
Dose & formulationPCOS Sisters +24
64
88
Clinical oversightiThriveMD +19
89
70
Labs & monitoringiThriveMD +39
91
52
FulfillmentiThriveMD +10
75
65
Contract termsiThriveMD +14
55
41
iThriveMD · left barPCOS Sisters · right bar

The numbers

MetriciThriveMDPCOS Sisters
WeighScore66.7/10065.7/100
GradeCC
Scorecard rank#186#219
Semaglutide$299/mo (starting dose, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$399/mo (starting dose, compounded)$150/mo (plus a separate fee, compounded)
CoverageCoverage not published12 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
iThriveMD

Graded #186 · C

Strengths

  • Compounded semaglutide (from $299/mo) and tirzepatide (from $399/mo), plus microdosing tirzepatide programs
  • Lab testing and personalized protocols with a medical team; free initial consultation
  • Very thorough legal/policy suite (Terms, Privacy, EUA, Shipping, Returns, CCPA)
  • Broad longevity menu: hormones (HRT/TRT), NAD+, peptides, IV therapy, sexual health, diagnostics

Where it loses points

  • Premium pricing — higher than budget compounded-GLP-1 competitors (lowest rates need 'preferred pricing')
  • Headline GLP-1 pricing is 'starting at'; full cost depends on dose and program length
  • Compounding pharmacy partner not named
  • Not LegitScript-certified (no certification displayed)
PCOS Sisters

Graded #219 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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