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Head-to-head · WeighScore

iThriveMD vs Knownwell

iThriveMD
Graded #186

Lower grade

vs+0.20000000000000284
Knownwell
Graded #180

Higher grade

The verdict

Knownwell takes it — 66.9/100 to 66.7/100, but only just.

Knownwell grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Knownwell is a weight-inclusive metabolic and primary care company co-founded by obesity-medicine specialist Dr. iThriveMD is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueKnownwell +2
36
38
Dose & formulationKnownwell +12
64
76
Clinical oversightKnownwell +1
89
90
Labs & monitoringiThriveMD +28
91
63
FulfillmentKnownwell +11
75
86
Contract termsEven
55
55
iThriveMD · left barKnownwell · right bar

The numbers

MetriciThriveMDKnownwell
WeighScore66.7/10066.9/100
GradeCC
Scorecard rank#186#180
Semaglutide$299/mo (starting dose, compounded)Not disclosed
Tirzepatide$399/mo (starting dose, compounded)$349/mo (brand Zepbound)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
iThriveMD

Graded #186 · C

Strengths

  • Compounded semaglutide (from $299/mo) and tirzepatide (from $399/mo), plus microdosing tirzepatide programs
  • Lab testing and personalized protocols with a medical team; free initial consultation
  • Very thorough legal/policy suite (Terms, Privacy, EUA, Shipping, Returns, CCPA)
  • Broad longevity menu: hormones (HRT/TRT), NAD+, peptides, IV therapy, sexual health, diagnostics

Where it loses points

  • Premium pricing — higher than budget compounded-GLP-1 competitors (lowest rates need 'preferred pricing')
  • Headline GLP-1 pricing is 'starting at'; full cost depends on dose and program length
  • Compounding pharmacy partner not named
  • Not LegitScript-certified (no certification displayed)
Knownwell

Graded #180 · C

Strengths

  • Co-founded by obesity-medicine specialist Dr. Angela Fitch
  • Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
  • Official LillyDirect provider and Novo Wegovy-pill telehealth partner
  • Accepts insurance, copays as low as $25 for covered patients
  • Weight-inclusive care with dietitians and health coaches

Where it loses points

  • Specific self-pay monthly medication prices not transparently posted
  • In-person clinics limited to four metro areas
  • Branded-only focus can mean higher cost than compounded routes

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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