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Head-to-head · WeighScore

Invyncible vs PCOS Sisters

Invyncible
Graded #303

Lower grade

vs+5
PCOS Sisters
Graded #211

Higher grade

The verdict

PCOS Sisters takes it — 66/100 to 61/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +7
55
62
Dose & formulationPCOS Sisters +24
64
88
Clinical oversightEven
70
70
Labs & monitoringEven
52
52
FulfillmentEven
65
65
Contract termsInvyncible +20
61
41
Invyncible · left barPCOS Sisters · right bar

The numbers

MetricInvynciblePCOS Sisters
WeighScore61/10066/100
GradeCC
Scorecard rank#303#211
Semaglutide$192/mo (0.5 mg dose, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$210/mo (compounded)$150/mo (plus a separate fee, compounded)
Coverage40 states12 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
Invyncible

Graded #303 · C

Strengths

  • Corporate parent disclosed (Nationwide Telemedicine, LLC) — better than most competitors hiding behind trade names
  • Physical corporate address published (St. Petersburg, FL)
  • LegitScript verification seal displayed
  • No long-term commitment required
  • Offers both semaglutide and tirzepatide programs

Where it loses points

  • Pricing not disclosed on the public site — fully gated behind signup
  • Drug forms (compounded vs brand, injection vs oral) not disclosed
  • 503A vs 503B designation not specified
  • Pharmacy partner not named
  • States served not listed publicly
PCOS Sisters

Graded #211 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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