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Head-to-head · WeighScore

Invyncible vs Jyra Health

Invyncible
Graded #303

Lower grade

vs+8.599999999999994
Jyra Health
Graded #117

Higher grade

The verdict

Jyra Health takes it — 69.6/100 to 61/100.

Jyra Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueJyra Health +17
55
72
Dose & formulationEven
64
64
Clinical oversightJyra Health +12
70
82
Labs & monitoringJyra Health +1
52
53
FulfillmentJyra Health +23
65
88
Contract termsInvyncible +12
61
49
Invyncible · left barJyra Health · right bar

The numbers

MetricInvyncibleJyra Health
WeighScore61/10069.6/100
GradeCC
Scorecard rank#303#117
Semaglutide$192/mo (0.5 mg dose, compounded)$99/mo (starting dose, plus a separate fee, compounded)
Tirzepatide$210/mo (compounded)$133/mo (starting dose, promotional rate, compounded)
Coverage40 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Invyncible

Graded #303 · C

Strengths

  • Corporate parent disclosed (Nationwide Telemedicine, LLC) — better than most competitors hiding behind trade names
  • Physical corporate address published (St. Petersburg, FL)
  • LegitScript verification seal displayed
  • No long-term commitment required
  • Offers both semaglutide and tirzepatide programs

Where it loses points

  • Pricing not disclosed on the public site — fully gated behind signup
  • Drug forms (compounded vs brand, injection vs oral) not disclosed
  • 503A vs 503B designation not specified
  • Pharmacy partner not named
  • States served not listed publicly
Jyra Health

Graded #117 · C

Strengths

  • Among the lowest compounded pricing — semaglutide from $99/mo and tirzepatide from $133/mo, with no membership and no hidden fees
  • Board-certified providers in all 50 states; no insurance required and free express delivery
  • Offers both compounded semaglutide and tirzepatide, plus a longevity track
  • Full legal suite published (Privacy, Terms, HIPAA, Refunds & Cancellations)

Where it loses points

  • The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
  • Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Zepbound, Ozempic, or Mounjaro
  • Displays a self-hosted LegitScript badge but no verifiable seal or listing
  • Compounding pharmacy not named; appears to be a newer, smaller clinic (~300 patients/month)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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