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Head-to-head · WeighScore

InstaRX vs Onyx Weight Loss

InstaRX
Graded #250

Higher grade

vs+5
Onyx Weight Loss
Graded #359

Lower grade

The verdict

InstaRX takes it — 63.8/100 to 58.8/100.

InstaRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. InstaRX is a multi-product compounded-medication telehealth platform offering GLP-1 injections (semaglutide and tirzepatide) alongside anti-aging peptides (NAD+, Sermorelin, B12/MIC) and sexual-health…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueInstaRX +17
60
43
Dose & formulationEven
64
64
Clinical oversightOnyx Weight Loss +3
72
75
Labs & monitoringOnyx Weight Loss +11
52
63
FulfillmentInstaRX +25
78
53
Contract termsEven
55
55
InstaRX · left barOnyx Weight Loss · right bar

The numbers

MetricInstaRXOnyx Weight Loss
WeighScore63.8/10058.8/100
GradeCC
Scorecard rank#250#359
Semaglutide$199/mo (starting dose, compounded)$228/mo (starting dose, compounded)
Tirzepatide$199/mo (starting dose, compounded)$280/mo (starting dose, compounded)
CoverageAll 50 states8 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
InstaRX

Graded #250 · C

Strengths

  • Available in all 50 states plus DC
  • Manage GLP-1, anti-aging peptides, and sexual-health medications on one account
  • Offers both compounded semaglutide and compounded tirzepatide
  • Independent provider group (Dr Telx) named in the Terms of Service

Where it loses points

  • No per-dose or monthly pricing published — only a "$199 to get started" hook; you can't compare costs before intake
  • No LegitScript, HIPAA, or NABP accreditation shown on public pages
  • Compounding pharmacy not named — only "U.S. pharmacies"
  • Terms of Service reads like generic boilerplate, including copy-paste language about women's health issues — suggests low template hygiene
  • Delaware governing law for disputes despite a California corporate address
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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