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Head-to-head · WeighScore

Immortals vs Lyfe Rx

Immortals
Graded #286

Higher grade

vs+3.5
Lyfe Rx
Graded #375

Lower grade

The verdict

Immortals takes it — 61.8/100 to 58.3/100.

Immortals grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Immortals is a LegitScript-certified longevity telehealth platform founded by Bryan Johnson, offering compounded semaglutide (Semaglutide/Glycine/B12) and tirzepatide (Tirzepatide/Glycine/B12) as microdose…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueImmortals +4
54
50
Dose & formulationEven
64
64
Clinical oversightImmortals +21
88
67
Labs & monitoringImmortals +2
54
52
FulfillmentImmortals +6
68
62
Contract termsLyfe Rx +35
20
55
Immortals · left barLyfe Rx · right bar

The numbers

MetricImmortalsLyfe Rx
WeighScore61.8/10058.3/100
GradeCC
Scorecard rank#286#375
Semaglutide$167/mo (microdose tier, compounded)$225/mo (compounded)
Tirzepatide$180/mo (microdose tier, compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Immortals

Graded #286 · C

Strengths

  • LegitScript certified (ID 50458743) with board-certified U.S. physician review within 72 hours
  • Physician consult + prescription bundled in price — 'You pay for treatment. That's it' with no added fees
  • Competitive pricing: semaglutide microdose from $167/month, tirzepatide from $180/month (promotional)
  • Unlimited provider messaging for 12 months included; video consults available
  • Founded by Bryan Johnson and Kate Tolo; clinical lead Dr. Carl Seger, M.D. (preventive/longevity medicine)

Where it loses points

  • Microdose framing uses sub-clinical doses — lower weight-loss efficacy than standard GLP-1 protocols
  • Quarterly commitment only — 3-month minimum, paid upfront ($501–$540/quarter); no monthly flexibility
  • State availability not publicly listed; 'eligible U.S. states' with no specific state list
  • Labs not included; baseline bloodwork protocol not disclosed on any public page
  • Compounding pharmacy not named; no 503A/503B accreditation details disclosed
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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