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Head-to-head · WeighScore

HumeCare+ vs Lyfe Rx

HumeCare+
Graded #366

Higher grade

vs+0.30000000000000426
Lyfe Rx
Graded #375

Lower grade

The verdict

HumeCare+ takes it — 58.6/100 to 58.3/100, but only just.

HumeCare+ grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. HumeCare+ is the GLP-1 telehealth program from Hume Health, the body-composition scale company. Lyfe Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueHumeCare+ +4
54
50
Dose & formulationLyfe Rx +12
52
64
Clinical oversightHumeCare+ +4
71
67
Labs & monitoringHumeCare+ +1
53
52
FulfillmentHumeCare+ +2
64
62
Contract termsHumeCare+ +6
61
55
HumeCare+ · left barLyfe Rx · right bar

The numbers

MetricHumeCare+Lyfe Rx
WeighScore58.6/10058.3/100
GradeCC
Scorecard rank#366#375
Semaglutide$199/mo (starting dose, compounded)$225/mo (compounded)
TirzepatideNot disclosed$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
HumeCare+

Graded #366 · C

Strengths

  • Pairs compounded semaglutide with continuous body-composition tracking (lose fat, preserve muscle)
  • Includes a Hume Pod body-composition device at no extra cost
  • From $199/mo, billed monthly, cancel anytime
  • Backed by Hume Health, an established body-composition scale brand
  • Clinician-prescribed and monitored with weekly tracking

Where it loses points

  • Final medication pricing is gated behind an intake quiz
  • Only semaglutide is shown on the marketing site (tirzepatide not confirmed)
  • Prescribing medical group and pharmacy partner not named
  • States of operation not published
  • Not LegitScript-certified (no certification displayed)
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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