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Head-to-head · WeighScore

Heros Health vs Lyfe Rx

Heros Health
Graded #194

Higher grade

vs+8
Lyfe Rx
Graded #375

Lower grade

The verdict

Heros Health takes it — 66.3/100 to 58.3/100.

Heros Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Heros Health is a direct-to-consumer telehealth platform offering compounded semaglutide and tirzepatide for weight loss on a flat program price — $149 the first month, then $199/mo (or $165/mo on a 3-month…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueHeros Health +10
60
50
Dose & formulationEven
64
64
Clinical oversightHeros Health +20
87
67
Labs & monitoringHeros Health +2
54
52
FulfillmentHeros Health +14
76
62
Contract termsLyfe Rx +6
49
55
Heros Health · left barLyfe Rx · right bar

The numbers

MetricHeros HealthLyfe Rx
WeighScore66.3/10058.3/100
GradeCC
Scorecard rank#194#375
Semaglutide$199/mo (compounded)$225/mo (compounded)
Tirzepatide$199/mo (compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Heros Health

Graded #194 · C

Strengths

  • Compounded semaglutide and tirzepatide on a flat program price, not tiered by dose
  • Transparent pricing: $149 first month, then $199/mo (or $165/mo on the 3-month plan)
  • 90-day money-back guarantee on GLP-1 treatment
  • Dose adjustments at weeks 2, 4, and 8 included at no extra cost
  • Named board-certified physicians (Dr. Amber Patel, Dr. Scott Sanderson, Dr. Scott Nass)

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Specific 503A pharmacy partner is not named publicly
  • State coverage is stated inconsistently on the site (claims both 50 and 46 states)
  • No insurance billing — cash-pay only
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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