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Head-to-head · WeighScore

HeliMeds vs PlexusDx

HeliMeds
Graded #148

Higher grade

vs+0.5999999999999943
PlexusDx
Graded #158

Lower grade

The verdict

HeliMeds takes it — 68.3/100 to 67.7/100, but only just.

HeliMeds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. HeliMeds offers compounded semaglutide and tirzepatide as well as brand-name Wegovy and Zepbound. PlexusDx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
74
74
Dose & formulationHeliMeds +13
77
64
Clinical oversightPlexusDx +3
71
74
Labs & monitoringEven
52
52
FulfillmentPlexusDx +11
67
78
Contract termsEven
55
55
HeliMeds · left barPlexusDx · right bar

The numbers

MetricHeliMedsPlexusDx
WeighScore68.3/10067.7/100
GradeCC
Scorecard rank#148#158
Semaglutide$1,599/mo (brand Wegovy)$149/mo (starting dose, compounded)
Tirzepatide$149/mo (starting dose, compounded)$249/mo (starting dose, compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
HeliMeds

Graded #148 · C

Strengths

  • Both compounded and brand-name GLP-1 options available
  • LegitScript certified (#368688)
  • Compounded semaglutide from $99 — competitive pricing

Where it loses points

  • State availability not publicly disclosed
  • Compounded medications are not FDA-approved (stated on site)
  • Also a broader health platform (sexual health, energy)
PlexusDx

Graded #158 · C

Strengths

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Where it loses points

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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