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Head-to-head · WeighScore

HealthOn vs Lyfe Rx

HealthOn
Graded #349

Higher grade

vs+0.8000000000000043
Lyfe Rx
Graded #375

Lower grade

The verdict

HealthOn takes it — 59.1/100 to 58.3/100, but only just.

HealthOn grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. HealthOn offers compounded semaglutide and tirzepatide starting at $155/month. Lyfe Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLyfe Rx +4
46
50
Dose & formulationEven
64
64
Clinical oversightHealthOn +12
79
67
Labs & monitoringEven
52
52
FulfillmentEven
62
62
Contract termsLyfe Rx +8
47
55
HealthOn · left barLyfe Rx · right bar

The numbers

MetricHealthOnLyfe Rx
WeighScore59.1/10058.3/100
GradeCC
Scorecard rank#349#375
Semaglutide$189/mo (starting dose, 12-month plan, compounded)$225/mo (compounded)
Tirzepatide$290/mo (starting dose, 12-month plan, compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
HealthOn

Graded #349 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Weight-loss pricing starts at $189/mo for compounded semaglutide

Where it loses points

  • No visible LegitScript certification or PCAB accreditation
  • State availability not publicly disclosed
  • Lowest advertised prices require a 12-month plan commitment
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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