Head-to-head · WeighScore
He & She MD vs Synergy Rx
The verdict
Synergy Rx takes it — 76.2/100 to 71.5/100.
Synergy Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | He & She MD | Synergy Rx |
|---|---|---|
| WeighScore | 71.5/100 | 76.2/100 |
| Grade | C | C |
| Scorecard rank | #91 | #41 |
| Semaglutide | $139/mo (starting dose, promotional rate, compounded) | From $199/mo |
| Tirzepatide | $199/mo (starting dose, compounded) | From $349/mo |
| Coverage | All 50 states | Not disclosed |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #91 · C
Strengths
- Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
- Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
- Only charged if medication is prescribed; no hidden fees
- Free expedited shipping and unlimited board-certified clinician access
- GLP-1 coaching, nutrition guidance, and in-app progress tracking
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
- Does not ship to Louisiana or to PO boxes
- Introductory pricing rises after the 6-month (or 3-month microdose) plan
- Cash-pay model — insurance billing not indicated
Graded #41 · C
Strengths
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- $100 welcome credit at checkout, and FSA/HSA eligible
Where it loses points
- Publishes no GLP-1 price anywhere on its own site
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
- No published cancellation or refund terms
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.