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Head-to-head · WeighScore

He & She MD vs Sesame Care

He & She MD
Graded #91

Lower grade

vs+16.299999999999997
Sesame Care
Graded #2

Higher grade

The verdict

Sesame Care takes it — 87.8/100 to 71.5/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSesame Care +30
54
84
Dose & formulationSesame Care +4
88
92
Clinical oversightSesame Care +10
84
94
Labs & monitoringSesame Care +22
62
84
FulfillmentHe & She MD +12
92
80
Contract termsSesame Care +51
41
92
He & She MD · left barSesame Care · right bar

The numbers

MetricHe & She MDSesame Care
WeighScore71.5/10087.8/100
GradeCB+
Scorecard rank#91#2
Semaglutide$139/mo (starting dose, promotional rate, compounded)From $149/mo (brand Wegovy pill)
Tirzepatide$199/mo (starting dose, compounded)Brand Zepbound (price varies)
CoverageAll 50 statesNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes
He & She MD

Graded #91 · C

Strengths

  • Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
  • Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
  • Only charged if medication is prescribed; no hidden fees
  • Free expedited shipping and unlimited board-certified clinician access
  • GLP-1 coaching, nutrition guidance, and in-app progress tracking

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
  • Does not ship to Louisiana or to PO boxes
  • Introductory pricing rises after the 6-month (or 3-month microdose) plan
  • Cash-pay model — insurance billing not indicated
Sesame Care

Graded #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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