Head-to-head · WeighScore
He & She MD vs Layla
The verdict
He & She MD takes it — 71.5/100 to 70.9/100, but only just.
He & She MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral) plus a microdose option, with brand-name… Layla is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | He & She MD | Layla |
|---|---|---|
| WeighScore | 71.5/100 | 70.9/100 |
| Grade | C | C |
| Scorecard rank | #91 | #101 |
| Semaglutide | $139/mo (starting dose, promotional rate, compounded) | $237/mo (all doses, compounded) |
| Tirzepatide | $199/mo (starting dose, compounded) | $199/mo (all doses, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Yes |
Graded #91 · C
Strengths
- Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
- Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
- Only charged if medication is prescribed; no hidden fees
- Free expedited shipping and unlimited board-certified clinician access
- GLP-1 coaching, nutrition guidance, and in-app progress tracking
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
- Does not ship to Louisiana or to PO boxes
- Introductory pricing rises after the 6-month (or 3-month microdose) plan
- Cash-pay model — insurance billing not indicated
Graded #101 · C
Strengths
- Oral semaglutide dropper option plus injectable semaglutide and tirzepatide, with a brand-name upgrade path
- Named Medical Director (Dr. Ruth Cohen) and 24-7 doctor messaging
- Quiz-based intake with fast three to five day shipping
Where it loses points
- Brand-inclusive GLP-1 program is expensive, starting around 1,299 dollars
- States served are not published on the site
- Support phone line uses a UK format, and the compounding pharmacy is not named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.