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Head-to-head · WeighScore

Harper Meds vs Silhouette MD

Harper Meds
Graded #82

Higher grade

vs+2.799999999999997
Silhouette MD
Graded #129

Lower grade

The verdict

Harper Meds takes it — 72.2/100 to 69.4/100.

Harper Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. DTC telehealth weight-loss program (Nexus Health Solutions LLC) offering flat-rate compounded semaglutide and tirzepatide, with the consultation, prescription, medication, and shipping bundled into one…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueHarper Meds +12
86
74
Dose & formulationSilhouette MD +3
72
75
Clinical oversightSilhouette MD +3
74
77
Labs & monitoringSilhouette MD +1
53
54
FulfillmentHarper Meds +9
76
67
Contract termsEven
55
55
Harper Meds · left barSilhouette MD · right bar

The numbers

MetricHarper MedsSilhouette MD
WeighScore72.2/10069.4/100
GradeCC
Scorecard rank#82#129
Semaglutide$149/mo$149/mo (compounded)
Tirzepatide$196/mo$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Harper Meds

Graded #82 · C

Strengths

  • Flat pricing — same cost at every dose, no escalation as you titrate up
  • All-inclusive: doctor consultation, prescription, medication, and free shipping in one price
  • LegitScript-certified; prescriptions reviewed by US-licensed M.D.s
  • Offers both compounded semaglutide ($149/mo) and tirzepatide ($196/mo)

Where it loses points

  • Membership fee is non-refundable once paid
  • Partner pharmacy is not publicly named
  • State availability not published (limited to 'certain states')
Silhouette MD

Graded #129 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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