Head-to-head · WeighScore
Harmony Wellness Clinic vs Vyora Wellness
The verdict
Harmony Wellness Clinic takes it — 60.9/100 to 60.5/100, but only just.
Harmony Wellness Clinic grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Harmony Wellness Clinic is a LegitScript-certified telehealth platform offering compounded semaglutide (GLP-1 + B12) and compounded tirzepatide (GLP-1/GIP + B12) for medically supervised weight loss. Vyora Wellness is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Harmony Wellness Clinic | Vyora Wellness |
|---|---|---|
| WeighScore | 60.9/100 | 60.5/100 |
| Grade | C | C |
| Scorecard rank | #309 | #322 |
| Semaglutide | $200/mo (starting dose, compounded) | $299/mo (compounded) |
| Tirzepatide | $250/mo (starting dose, compounded) | $399/mo (compounded) |
| Coverage | 36 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #309 · C
Strengths
- LegitScript certified with licensed APRN-CNP clinical oversight by Kristina Stout
- Two compounded GLP-1 options: semaglutide+B12 (5 dose levels) and tirzepatide+B12 (6 dose levels)
- Partners with four named 503A compounding pharmacies for a transparent supply chain
- Competitive starting prices: $200/month for semaglutide and $250/month for tirzepatide
- Telehealth services available in 36 states via the Optimantra online patient portal
Where it loses points
- 36-state coverage — many states including some large markets not served
- Care led by APRN-CNP, not an MD or DO; no physician name disclosed
- Pricing scales with dose level up to $300/month (sema) and $450/month (tirz)
- Labs not mentioned or included on any public page — baseline bloodwork protocol unknown
- No coaching or lifestyle program disclosed beyond clinical dose management
Graded #322 · C
Strengths
- LegitScript certified
- Price includes nutritional guidance, 24/7 coaching, and community access
- Both semaglutide and tirzepatide available
- BMI 25+ eligibility threshold (lower than some competitors)
Where it loses points
- State availability not publicly disclosed
- Pricing is above average ($299–$399/mo) compared to competitors
- Compounded only — no brand-name options
- Broader platform (metabolic, longevity, topical products)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.