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Head-to-head · WeighScore

Genesis Health vs Open Water Rx

Genesis Health
Graded #150

Higher grade

vs+9.400000000000006
Open Water Rx
Graded #360

Lower grade

The verdict

Genesis Health takes it — 68.2/100 to 58.8/100.

Genesis Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueGenesis Health +4
52
48
Dose & formulationOpen Water Rx +11
77
88
Clinical oversightGenesis Health +35
89
54
Labs & monitoringGenesis Health +3
63
60
FulfillmentGenesis Health +31
73
42
Contract termsOpen Water Rx +8
47
55
Genesis Health · left barOpen Water Rx · right bar

The numbers

MetricGenesis HealthOpen Water Rx
WeighScore68.2/10058.8/100
GradeCC
Scorecard rank#150#360
Semaglutide$175/mo (starting dose, compounded)$249/mo (compounded)
Tirzepatide$235/mo (starting dose, compounded)$339/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessYesYes
Oral / sublingualInjection onlyYes
Genesis Health

Graded #150 · C

Strengths

  • Annual plan as low as $99/mo for semaglutide or $125/mo for tirzepatide
  • Offers both compounded and brand-name GLP-1s (Wegovy, Ozempic, Zepbound) in one platform
  • Includes health coaching, active community, and free expedited shipping on every plan
  • LegitScript certified; medications sourced from audited, licensed US compounding pharmacies
  • Same-day provider visits, personalized dosing, and 24/7 care team messaging

Where it loses points

  • States served not publicly listed; telehealth coverage unconfirmed for all states
  • Monthly starting price ($175 sema / $235 tirz) is mid-market without annual commitment
  • Labs not disclosed or included in any published plan tier
  • Brand-name GLP-1 pricing not published; insurance or coupon required
  • Compounded medications are not FDA-approved
Open Water Rx

Graded #360 · C

Strengths

  • Combines weight-loss and longevity verticals in one brand
  • Established brand domain

Where it loses points

  • Limited public data — most details are gated behind signup or rendered only in JavaScript
  • Pricing not disclosed
  • GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
  • States-served list not disclosed
  • Pharmacy partner not named

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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