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Head-to-head · WeighScore

Genesis Lifestyle Medicine vs Vyora Wellness

Genesis Lifestyle Medicine
Graded #392

Lower grade

vs+2.799999999999997
Vyora Wellness
Graded #321

Higher grade

The verdict

Vyora Wellness takes it — 60.5/100 to 57.7/100.

Vyora Wellness grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Vyora Wellness offers compounded semaglutide ($299/mo) and compounded tirzepatide ($399/mo) as 4-week subscription plans.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueGenesis Lifestyle Medicine +3
45
42
Dose & formulationVyora Wellness +11
53
64
Clinical oversightVyora Wellness +1
78
79
Labs & monitoringVyora Wellness +8
52
60
FulfillmentEven
67
67
Contract termsEven
55
55
Genesis Lifestyle Medicine · left barVyora Wellness · right bar

The numbers

MetricGenesis Lifestyle MedicineVyora Wellness
WeighScore57.7/10060.5/100
GradeCC
Scorecard rank#392#321
SemaglutideNot disclosed$299/mo (compounded)
TirzepatideNot disclosed$399/mo (compounded)
Coverage8 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only

Strengths

  • 18 physical clinics allow in-person consults and injections across 8 states
  • Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
  • Med spa model lets patients combine weight loss, hormone therapy, and aesthetics
  • Established brand with an 18-location footprint and patient testimonials
  • Telehealth available for remote patients in served states

Where it loses points

  • Pricing not disclosed publicly — gated behind the consultation flow
  • Specific 503A/503B pharmacy partner not named, and the designation not specified
  • No FDA compounded-medication disclaimer visible on the homepage
  • Named medical director not formally disclosed (only a 'Dr. Spinoso' testimonial)
  • Corporate legal entity and governing law not disclosed
Vyora Wellness

Graded #321 · C

Strengths

  • LegitScript certified
  • Price includes nutritional guidance, 24/7 coaching, and community access
  • Both semaglutide and tirzepatide available
  • BMI 25+ eligibility threshold (lower than some competitors)

Where it loses points

  • State availability not publicly disclosed
  • Pricing is above average ($299–$399/mo) compared to competitors
  • Compounded only — no brand-name options
  • Broader platform (metabolic, longevity, topical products)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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