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Head-to-head · WeighScore

Genesis Lifestyle Medicine vs SynergenX Health

Genesis Lifestyle Medicine
Graded #392

Lower grade

vs+0.6999999999999957
SynergenX Health
Graded #374

Higher grade

The verdict

SynergenX Health takes it — 58.4/100 to 57.7/100, but only just.

SynergenX Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. SynergenX Health is a multi-state hormone and weight-loss clinic chain with 64 locations across 10 states offering a telehealth GLP-1 program currently available to Texas patients. Genesis Lifestyle Medicine is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSynergenX Health +1
45
46
Dose & formulationGenesis Lifestyle Medicine +1
53
52
Clinical oversightGenesis Lifestyle Medicine +12
78
66
Labs & monitoringSynergenX Health +34
52
86
FulfillmentGenesis Lifestyle Medicine +12
67
55
Contract termsGenesis Lifestyle Medicine +8
55
47
Genesis Lifestyle Medicine · left barSynergenX Health · right bar

The numbers

MetricGenesis Lifestyle MedicineSynergenX Health
WeighScore57.7/10058.4/100
GradeCC
Scorecard rank#392#374
SemaglutideNot disclosed$150/mo (starting dose, plus a separate fee, compounded)
TirzepatideNot disclosedNot disclosed
Coverage8 states10 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only

Strengths

  • 18 physical clinics allow in-person consults and injections across 8 states
  • Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
  • Med spa model lets patients combine weight loss, hormone therapy, and aesthetics
  • Established brand with an 18-location footprint and patient testimonials
  • Telehealth available for remote patients in served states

Where it loses points

  • Pricing not disclosed publicly — gated behind the consultation flow
  • Specific 503A/503B pharmacy partner not named, and the designation not specified
  • No FDA compounded-medication disclaimer visible on the homepage
  • Named medical director not formally disclosed (only a 'Dr. Spinoso' testimonial)
  • Corporate legal entity and governing law not disclosed
SynergenX Health

Graded #374 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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