Head-to-head · WeighScore
Genesis Lifestyle Medicine vs PlexusDx
The verdict
PlexusDx takes it — 67.7/100 to 57.7/100.
PlexusDx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Genesis Lifestyle Medicine | PlexusDx |
|---|---|---|
| WeighScore | 57.7/100 | 67.7/100 |
| Grade | C | C |
| Scorecard rank | #392 | #161 |
| Semaglutide | Not disclosed | $149/mo (starting dose, compounded) |
| Tirzepatide | Not disclosed | $249/mo (starting dose, compounded) |
| Coverage | 8 states | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #392 · C
Strengths
- 18 physical clinics allow in-person consults and injections across 8 states
- Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
- Med spa model lets patients combine weight loss, hormone therapy, and aesthetics
- Established brand with an 18-location footprint and patient testimonials
- Telehealth available for remote patients in served states
Where it loses points
- Pricing not disclosed publicly — gated behind the consultation flow
- Specific 503A/503B pharmacy partner not named, and the designation not specified
- No FDA compounded-medication disclaimer visible on the homepage
- Named medical director not formally disclosed (only a 'Dr. Spinoso' testimonial)
- Corporate legal entity and governing law not disclosed
Graded #161 · C
Strengths
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
Where it loses points
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.