Head-to-head · WeighScore
Genesis Lifestyle Medicine vs Nucific
The verdict
Genesis Lifestyle Medicine takes it — 57.7/100 to 56.2/100, but only just.
Genesis Lifestyle Medicine grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Genesis Lifestyle Medicine is a hybrid in-office and telehealth medical spa with 18 clinic locations across 8 states, offering brick-and-mortar accountability uncommon among DTC GLP-1 providers. Nucific is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Genesis Lifestyle Medicine | Nucific |
|---|---|---|
| WeighScore | 57.7/100 | 56.2/100 |
| Grade | C | C |
| Scorecard rank | #392 | #418 |
| Semaglutide | Not disclosed | Not disclosed |
| Tirzepatide | Not disclosed | Not disclosed |
| Coverage | 8 states | Coverage not published |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #392 · C
Strengths
- 18 physical clinics allow in-person consults and injections across 8 states
- Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
- Med spa model lets patients combine weight loss, hormone therapy, and aesthetics
- Established brand with an 18-location footprint and patient testimonials
- Telehealth available for remote patients in served states
Where it loses points
- Pricing not disclosed publicly — gated behind the consultation flow
- Specific 503A/503B pharmacy partner not named, and the designation not specified
- No FDA compounded-medication disclaimer visible on the homepage
- Named medical director not formally disclosed (only a 'Dr. Spinoso' testimonial)
- Corporate legal entity and governing law not disclosed
Graded #418 · C
Strengths
- Founder is named and credentialed: Dr. Amy Lee, MD, triple board-certified in Internal Medicine, Obesity Medicine and Clinical Nutrition
- Cites SURMOUNT-1 properly, naming the trial, the 20.9% average and the Jastreboff NEJM 2022 source
- Discloses that featured patients were compensated for their time
- Labels its NAD+ decline chart as illustrative and not a measurement, with an unusually careful methodology note
- Offers compounded, microdosed and brand-name Ozempic and Zepbound in one catalogue
Where it loses points
- No price is published anywhere; every option is gated behind a three-minute quiz
- The LegitScript badge is a self-hosted image with generic alt text rather than the issued embed, so the certification could not be verified
- A BBB Accredited A+ claim is displayed without a link to the BBB profile
- No state list and no named pharmacy, only licensed U.S. pharmacies
- Before-and-after photographs are used alongside compensated testimonials
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.