Head-to-head · WeighScore
Genesis Lifestyle Medicine vs Lyfe Rx
The verdict
Lyfe Rx takes it — 58.3/100 to 57.7/100, but only just.
Lyfe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399). Genesis Lifestyle Medicine is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Genesis Lifestyle Medicine | Lyfe Rx |
|---|---|---|
| WeighScore | 57.7/100 | 58.3/100 |
| Grade | C | C |
| Scorecard rank | #392 | #375 |
| Semaglutide | Not disclosed | $225/mo (compounded) |
| Tirzepatide | Not disclosed | $299/mo (compounded) |
| Coverage | 8 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #392 · C
Strengths
- 18 physical clinics allow in-person consults and injections across 8 states
- Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
- Med spa model lets patients combine weight loss, hormone therapy, and aesthetics
- Established brand with an 18-location footprint and patient testimonials
- Telehealth available for remote patients in served states
Where it loses points
- Pricing not disclosed publicly — gated behind the consultation flow
- Specific 503A/503B pharmacy partner not named, and the designation not specified
- No FDA compounded-medication disclaimer visible on the homepage
- Named medical director not formally disclosed (only a 'Dr. Spinoso' testimonial)
- Corporate legal entity and governing law not disclosed
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.